Research Scholars Seminar Series
- February 28, 2023
- 3:00 PM - 4:00 CST
- WEBINAR
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OFFICE OF THE VICE PROVOST FOR RESEARCH
SAMANTHA BYNUM, sbynum1@luc.edu - Open to the public.
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Details
Dr. Rocco Gogliotti, PhD
*Drug Discovery for Neurodevelopmental Disorders: Putting the Patient First*
The success rate of compounds entering clinical trials for neurological disorders has fallen sharply in recent years. Dr. Gogliotti's lab has chosen to address this problem by coupling advancements in next-generation sequencing technologies with human autopsy samples to facilitate target identification. This bedside-to-bench approach emphasizes establishing translational relevance early in study design, with the mission of replacing the *more shots on goal* approach to therapeutic development with one that emphasizes *better shots on goal*. Dr. Gogliotti will share his group¿s research that led to the identification of muscarinic acetylcholine receptors, heat shock proteins, and regulatory microRNAs as potential therapeutic targets for the neurodevelopmental disorder Rett syndrome.t is, how this project mitigates health disparities, and health equity research design
